Dorizoe offers proven expertise in providing regulatory-compliant product development services for the following dosage forms in Topical/Ophthalmic category:

  • Ointment
  • Cream
  • Gel
  • Lotion
  • Solutions
  • Suspensions
  • Emulsions

With the backend support from a talented analytical group, our formulation team is prepared to address all aspects of product development, including:

  • Physical and chemical characterization
  • Formulation development
  • Container/closure and delivery component compatibility
  • Drug product stability testing
  • Scale-up and technology transfer

Services include feasibility studies and compatibility studies of active ingredients with excipients and delivery components. Formulation selection and optimization are aided by the extensive use of statistical experimental design. Short-term and accelerated stability studies are typically employed to challenge the candidate formulations.

A variety of formulation tests and services are offered to understand the physical and chemical characteristics of the dosage form. These include:

  • Particle size and morphology
  • Partition coefficient
  • Wettability
    • Release profile, in vitro permeation rate, homogeneity
    • Stability profile
    • Package compatibility
    • Antimicrobial preservatives
    • Temperature cycling study
    • Viscosity and spreadability

Our formulation scientists, in collaboration with CMO, develop a manufacturing process, which can be optimized for robustness and efficiency, then scaled up through careful evaluation of manufacturing parameters. We coordinate our clients for successful technology transfer to CMO for scale up and registration batches.

We welcome the opportunity to discuss topical/ophthalmic product development opportunities and how our proven expertise and technologies can help reduce the risk and increase the chances of product success.

    Dorizoe Lifesciences

    (A Business Unit of Altheon Enterprises Ltd.)
  •   Claris Corporate Headquarters
    Nr. Parimal Crossing, Ellisbridge,
    Ahmedabad - 380 006.
    Gujarat ( INDIA )